| Title | Effects induced in vitro by Aflatoxin B1 on Vibrio fischeri and on primary cultures of Sparus aurata hepatocytes. |
| Abstract | Among biotoxins, aflatoxins represent one of the most investigated, widespread and worrisome source of contamination of feed worldwide. Even if these compounds exert a substantial impact on the fish farming production, causing diseases with high mortality, as well as gradual decline of reared fish stock quality, metabolic and toxicological studies in marine aquacultured species are fragmented and restricted. The aim of this study was to investigate the effects induced in vitro by aflatoxin B1 (AFB1) on Vibrio fischeri, using the Microtox® system, and on Sparus aurata hepatocytes, in order to screen the toxicity range, and the boundary between acute and subacute toxicity, using different test systems in order to provide new information on the exposure risk of S. aurata to AFB1 contaminated feedstuffs. |
| Source | Chemistry and ecology (Online) 27 (2), pp. 67–76 |
| Journal | Chemistry and ecology (Online) |
| Editor | Gordon and Breach Publishing Group., Amsterdam, Paesi Bassi |
| Year | 2011 |
| Type | Articolo in rivista |
| Authors | Santacroce M.P.2, Narracci M.1, Acquaviva M.I.1, Zacchino V.2, Lo Noce R.1, Centoducati G.2, R.A. Cavallo. |
| Text | 75210 2011 Effects induced in vitro by Aflatoxin B1 on Vibrio fischeri and on primary cultures of Sparus aurata hepatocytes. Santacroce M.P.2, Narracci M.1, Acquaviva M.I.1, Zacchino V.2, Lo Noce R.1, Centoducati G.2, R.A. Cavallo. 1Institute for Coastal Marine Environment, National Research Council of Italy, Taranto, Italy 2Department of Public Health and Animal Science, Division of Aquaculture, Faculty of Veterinary Medicine, University of Bari, Italy Among biotoxins, aflatoxins represent one of the most investigated, widespread and worrisome source of contamination of feed worldwide. Even if these compounds exert a substantial impact on the fish farming production, causing diseases with high mortality, as well as gradual decline of reared fish stock quality, metabolic and toxicological studies in marine aquacultured species are fragmented and restricted. The aim of this study was to investigate the effects induced in vitro by aflatoxin B1 AFB1 on Vibrio fischeri, using the Microtox® system, and on Sparus aurata hepatocytes, in order to screen the toxicity range, and the boundary between acute and subacute toxicity, using different test systems in order to provide new information on the exposure risk of S. aurata to AFB1 contaminated feedstuffs. 27 Articolo in rivista Gordon and Breach Publishing Group. 1029 0370 Chemistry and ecology Online Chemistry and ecology Online Chem. ecol. Online mariaimmacolata.acquaviva ACQUAVIVA MARIA IMMACOLATA marcella.narracci NARRACCI MARCELLA rosaanna.cavallo CAVALLO ROSA ANNA TA.P05.016.002 Ricerca e Applicazione di metodologie eco tossicologiche per la valutazione della qualita di ambienti acquatici |
