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DatoValore
TitlePHARMACEUTICALS AS PRIORITY WATER CONTAMINANTS
AbstractPharmaceuticals and their metabolites can reach water bodies through sewage systems, industrial discharges, effluents from sewage treatment plants (STPs), aquaculture, and livestock farming. Pharmaceuticals include a hundred substances which are very different as regards chemical-physical properties and environmental behavior, although they may have strong biochemical activities. At present, pharmaceuticals can reach water concentrations of ng L-1 to ?g L-1 and some are considered ubiquitous. Nevertheless, their presence in the aquatic environment and impact on aquatic biota and on human health have not yet been studied adequately. Experimental evidence indicates that pharmaceuticals may cause harmful effects, such as morphological, metabolic and sex alterations on aquatic species, induction of antibiotic resistance in aquatic pathogenic microorganisms, and disruption of biodegradation activities in STPs. Risk assessment studies and evaluations are in progress. Yet, the available scientific data are consistent with the introduction of some pharmaceutical indicators in extensive water monitoring to better define their actual impact on aquatic organisms and humans. Under these perspectives, the inclusion of emerging pharmaceuticals in the revision of EU List of Priority Substances under the Water Framework Directive 2000/60/EC should be implemented as well as the definition of respective environmental quality standards
SourceToxicological and environmental chemistry (Print) 92 (3), pp. 549–565
JournalToxicological and environmental chemistry (Print)
EditorGordon and Breach Science Publishers., New York, Stati Uniti d'America
Year2010
TypeArticolo in rivista
DOI10.1080/02772241003614320
AuthorsBOTTONI P. (a); CAROLI S. (b); BARRA CARACCIOLO A. (c)
Text67873 2010 10.1080/02772241003614320 Scopus 2 s2.0 77949363020 PHARMACEUTICALS AS PRIORITY WATER CONTAMINANTS BOTTONI P. a ; CAROLI S. b ; BARRA CARACCIOLO A. c a Department of Environment and Primary Prevention, Istituto Superiore di Sanita, Rome, Italy; b Department of Food Safety and Veterinary Public Health, Istituto Superiore di Sanita, Rome, Italy; c Water Research Institute, National Council of Research, Rome, Italy Pharmaceuticals and their metabolites can reach water bodies through sewage systems, industrial discharges, effluents from sewage treatment plants STPs , aquaculture, and livestock farming. Pharmaceuticals include a hundred substances which are very different as regards chemical physical properties and environmental behavior, although they may have strong biochemical activities. At present, pharmaceuticals can reach water concentrations of ng L 1 to g L 1 and some are considered ubiquitous. Nevertheless, their presence in the aquatic environment and impact on aquatic biota and on human health have not yet been studied adequately. Experimental evidence indicates that pharmaceuticals may cause harmful effects, such as morphological, metabolic and sex alterations on aquatic species, induction of antibiotic resistance in aquatic pathogenic microorganisms, and disruption of biodegradation activities in STPs. Risk assessment studies and evaluations are in progress. Yet, the available scientific data are consistent with the introduction of some pharmaceutical indicators in extensive water monitoring to better define their actual impact on aquatic organisms and humans. Under these perspectives, the inclusion of emerging pharmaceuticals in the revision of EU List of Priority Substances under the Water Framework Directive 2000/60/EC should be implemented as well as the definition of respective environmental quality standards 92 Articolo pubblicato TECPharm2010.pdf Articolo in rivista Gordon and Breach Science Publishers. 0277 2248 Toxicological and environmental chemistry Print Toxicological and environmental chemistry Print Toxicol. environ. chem. Print Toxicological and environmental chemistry. Print anna.barracaracciolo BARRA CARACCIOLO ANNA TA.P04.005.007 Strumenti di mitigazione dello stress quali quantitativo per i sistemi idrici