Scheda di dettaglio – i prodotti della ricerca
| Dato | Valore |
|---|---|
| Title | Antimicrobial Resistance in Rivers: A Review of the Genes Detected and New Challenges |
| Abstract | River ecosystems are very important parts of the water cycle and an excellent habitat, food, and drinking water source for many organisms, including humans. Antibiotics are emerging contaminants which can enter rivers from various sources. Several antibiotics and their related antibiotic resistance genes (ARGs) have been detected in these ecosystems by various research programs and could constitute a substantial problem. The presence of antibiotics and other resistance cofactors can boost the development of ARGs in the chromosomes or mobile genetic elements of natural bacteria in rivers. The ARGs in environmental bacteria can also be transferred to clinically important pathogens. However, antibiotics and their resistance genes are both not currently monitored by national or international authorities responsible for controlling the quality of water bodies. For example, they are not included in the contaminant list in the European Water Framework Directive or in the US list of Water-Quality Benchmarks for Contaminants. Although ARGs are naturally present in the environment, very few studies have focused on non-impacted rivers to assess the background ARG levels in rivers, which could provide some useful indications for future environmental regulation and legislation. The present study reviews the antibiotics and associated ARGs most commonly measured and detected in rivers, including the primary analysis tools used for their assessment. In addition, other factors that could enhance antibiotic resistance, such as the effects of chemical mixtures, the effects of climate change, and the potential effects of the coronavirus disease 2019 pandemic, are discussed. Environ Toxicol Chem 2022;00:1-27. (c) 2022 SETAC |
| Source | Environmental toxicology and chemistry 41 (3), pp. 687–714 |
| Keywords | Environmental bacteriaOne Health ApproachRiver monitoringMixing chemical effectsClimate changePandemic effects on antibiotic resistance |
| Journal | Environmental toxicology and chemistry |
| Editor | Pergamon,, New York, Stati Uniti d'America |
| Year | 2022 |
| Type | Articolo in rivista |
| DOI | 10.1002/etc.5289 |
| Authors | Grenni, Paola |
| Text | 465052 2022 10.1002/etc.5289 ISI Web of Science WOS 000758680600001 Environmental bacteria One Health Approach River monitoring Mixing chemical effects Climate change Pandemic effects on antibiotic resistance Antimicrobial Resistance in Rivers A Review of the Genes Detected and New Challenges Grenni, Paola Natl Res Council Italy River ecosystems are very important parts of the water cycle and an excellent habitat, food, and drinking water source for many organisms, including humans. Antibiotics are emerging contaminants which can enter rivers from various sources. Several antibiotics and their related antibiotic resistance genes ARGs have been detected in these ecosystems by various research programs and could constitute a substantial problem. The presence of antibiotics and other resistance cofactors can boost the development of ARGs in the chromosomes or mobile genetic elements of natural bacteria in rivers. The ARGs in environmental bacteria can also be transferred to clinically important pathogens. However, antibiotics and their resistance genes are both not currently monitored by national or international authorities responsible for controlling the quality of water bodies. For example, they are not included in the contaminant list in the European Water Framework Directive or in the US list of Water Quality Benchmarks for Contaminants. Although ARGs are naturally present in the environment, very few studies have focused on non impacted rivers to assess the background ARG levels in rivers, which could provide some useful indications for future environmental regulation and legislation. The present study reviews the antibiotics and associated ARGs most commonly measured and detected in rivers, including the primary analysis tools used for their assessment. In addition, other factors that could enhance antibiotic resistance, such as the effects of chemical mixtures, the effects of climate change, and the potential effects of the coronavirus disease 2019 pandemic, are discussed. Environ Toxicol Chem 2022;00 1 27. c 2022 SETAC 41 Published version 06/01/2022 Articolo pubblicato pdf Enviro Toxic and Chemistry 2022 Grenni Antimicrobial Resistance in Rivers A Review of the Genes Detected and New 1 .pdf Articolo in rivista Pergamon, 0730 7268 Environmental toxicology and chemistry Environmental toxicology and chemistry Environ. toxicol. chem. Environmental toxicology and chemistry paola.grenni GRENNI PAOLA |