| Abstract | The Fenton process activated by Zero Valent Iron (ZVI-Fenton) is shown here to effectively remove antibiotics reserved for hospital settings (specifically used to treat antibiotic-resistant infections) from wastewater, thereby helping in the fight against bacterial resistance. Effective degradation of cefazolin, imipenem and vancomycin in real urban wastewater was achieved at pH 5, which is quite near neutrality when compared with classic Fenton that works effectively at pH 3-4. The possibility to operate successfully at pH 5 has several advantages compared to operation at lower pH values: (i) lower reagent costs for pH adjustment; (ii) insignificant impact on wastewater conductivity, because lesser acid is required to acidify and lesser or no base for neutralization; (iii) undetectable release of dissolved Fe, which could otherwise be an issue for wastewater quality. The cost of reagents for the treatment ranges between 0.04 and 0.07 $ m, which looks very suitable for practical applications. The structures of the degradation intermediates of the studied antibiotics and their likely abundance suggest that, once the primary compound is eliminated, most of the potential to trigger antibiotic action has been removed. Application of the ZVI-Fenton technique to wastewater treatment could considerably lower the possibility for antibiotics to trigger the development of resistance in bacteria. |
| Text | 461371 2021 10.1016/j.chemosphere.2021.131170 Scopus 2 s2.0 85108442921 antibiotic resistance Elimination from wastewater of antibiotics reserved for hospital settings, with a Fenton process based on zero valent iron Furia F.; Minella M.; Gosetti F.; Turci F.; Sabatino R.; Di Cesare A.; Corno G.; Vione D. Dipartimento di Chimica, Universita di Torino, Via Pietro Giuria 5,9, Torino, 10125, Dipartimento di Chimica, Universita di Torino, Via Pietro Giuria 5,9, 10125 Torino, Italy., , Italy; Dipartimento di Scienze Dell Ambiente e Della Terra, Universita di Milano Bicocca, Piazza Della Scienza 1, Milano, 20126, Dipartimento di Scienze dell Ambiente e della Terra, Universita di Milano Bicocca, Piazza della Scienza 1, 20126 Milano, Italy., , Italy; Molecular Ecology Group, National Research Council of Italy, Water Research Institute, Largo Tonolli 50, Verbania, VCO, 28922, Molecular Ecology Group, National Research Council of Italy, Water Research Institute, Largo Tonolli 50, 28922, Verbania VCO , Italy., , Italy The Fenton process activated by Zero Valent Iron ZVI Fenton is shown here to effectively remove antibiotics reserved for hospital settings specifically used to treat antibiotic resistant infections from wastewater, thereby helping in the fight against bacterial resistance. Effective degradation of cefazolin, imipenem and vancomycin in real urban wastewater was achieved at pH 5, which is quite near neutrality when compared with classic Fenton that works effectively at pH 3 4. The possibility to operate successfully at pH 5 has several advantages compared to operation at lower pH values i lower reagent costs for pH adjustment; ii insignificant impact on wastewater conductivity, because lesser acid is required to acidify and lesser or no base for neutralization; iii undetectable release of dissolved Fe, which could otherwise be an issue for wastewater quality. The cost of reagents for the treatment ranges between 0.04 and 0.07 $ m, which looks very suitable for practical applications. The structures of the degradation intermediates of the studied antibiotics and their likely abundance suggest that, once the primary compound is eliminated, most of the potential to trigger antibiotic action has been removed. Application of the ZVI Fenton technique to wastewater treatment could considerably lower the possibility for antibiotics to trigger the development of resistance in bacteria. 283 Published version http //www.scopus.com/record/display.url eid=2 s2.0 85108442921 origin=inward Articolo in rivista Elsevier 0045 6535 Chemosphere Chemosphere Chemosphere Chemosphere. Chemosphere. Environmental chemistry, Chemosphere. Persistent organic pollutants and dioxins, Chemosphere. Environmental toxicology and risk assessment, Chemosphere. Science for Environmental toxicology, gianluca.corno CORNO GIANLUCA andrea.dicesare DI CESARE ANDREA |
