| Abstract | Marine invertebrates represent a vast, untapped source of bioactive compounds. Cnidarians are represented by nearly 10,000 species that contain a complex mixture of venoms, collagen, and other bioactive compounds, including enzymes, oligosaccharides, fatty acids, and lipophilic molecules. Due to their high abundance in coastal waters, several jellyfish taxa may be regarded as candidate targets for the discovery of novel lead molecules and biomaterials and as a potential source of food/feed ingredients. The moon jellyfish Aurelia coerulea is one of the most common jellyfish worldwide and is particularly abundant in sheltered coastal lagoons and marinas of the Mediterranean Sea, where it first appeared--as an alien species--in the last century, when Pacific oyster cultivation began. In the present study, the antioxidant and lysozyme antibacterial activities associated with extracts from different medusa compartments--namely the umbrella, oral arms, and secreted mucus--were investigated. Extracts from the oral arms of A. coerulea displayed significant antioxidant activity. Similarly, lysozyme-like activity was the highest in extracts from oral arms. These findings suggest that A. coerulea outbreaks may be used in the search for novel cytolytic and cytotoxic products against marine bacteria. The geographically wide occurrence and the seasonally high abundance of A. coerulea populations in coastal waters envisage and stimulate the search for biotechnological applications of jellyfish biomasses in the pharmaceutical, nutritional, and nutraceutical sectors. |
| Text | 459314 2021 10.3390/md19110619 Scopus 2 s2.0 85118718513 bioactive compounds antimicrobial compounds lysozyme like activity peptides moon medusa Jellyfish bioprospecting in the mediterranean sea Antioxidant and lysozyme like activities from Aurelia coerulea Cnidaria, Scyphozoa extracts Stabili L.; Rizzo L.; Caprioli R.; Leone A.; Piraino S. Department of Biological and Environmental Sciences and Technologies, University of Salento, Via Prov.le Lecce Monteroni, Lecce, 73100, Department of Biological and Environmental Sciences and Technologies, University of Salento, Via Prov.le Lecce Monteroni, 73100, Lecce, Italy, , Italy; Institute of Water Research, National Research Council, S.S. di Taranto, Via Roma 3, Taranto, 74123, Institute of Water Research, National Research Council, S.S. di Taranto, Via Roma 3, 74123, Taranto, Italy, , Italy; Department of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, Villa Comunale, Napoli, 80121, Department of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121, Napoli, Italy, , Italy; Institute of Sciences of Food Production, National Research Council CNR ISPA , Via Prov.le Lecce Monteroni, Lecce, 72100, Institute of Sciences of Food Production, National Research Council CNR ISPA , Via Prov.le Lecce Monteroni, 72100, Lecce, Italy, , Italy; Consorzio Nazionale Interuniversitario per le Scienze del Mare CoNISMa , Piazzale Flaminio 9, Roma, 00196, Consorzio Nazionale Interuniversitario per le Scienze del Mare CoNISMa , Piazzale Flaminio 9, 00196, Roma, Italy, , Italy Marine invertebrates represent a vast, untapped source of bioactive compounds. Cnidarians are represented by nearly 10,000 species that contain a complex mixture of venoms, collagen, and other bioactive compounds, including enzymes, oligosaccharides, fatty acids, and lipophilic molecules. Due to their high abundance in coastal waters, several jellyfish taxa may be regarded as candidate targets for the discovery of novel lead molecules and biomaterials and as a potential source of food/feed ingredients. The moon jellyfish Aurelia coerulea is one of the most common jellyfish worldwide and is particularly abundant in sheltered coastal lagoons and marinas of the Mediterranean Sea, where it first appeared as an alien species in the last century, when Pacific oyster cultivation began. In the present study, the antioxidant and lysozyme antibacterial activities associated with extracts from different medusa compartments namely the umbrella, oral arms, and secreted mucus were investigated. Extracts from the oral arms of A. coerulea displayed significant antioxidant activity. Similarly, lysozyme like activity was the highest in extracts from oral arms. These findings suggest that A. coerulea outbreaks may be used in the search for novel cytolytic and cytotoxic products against marine bacteria. The geographically wide occurrence and the seasonally high abundance of A. coerulea populations in coastal waters envisage and stimulate the search for biotechnological applications of jellyfish biomasses in the pharmaceutical, nutritional, and nutraceutical sectors. 19 Published version http //www.scopus.com/record/display.url eid=2 s2.0 85118718513 origin=inward 29/10/2021 Jellyfish Bioprospecting in the Mediterranean Sea Antioxidant and Lysozyme Like Activities from Aurelia coerulea Cnidaria, Scyphozoa Extracts Stabili et al., 2021 Stabili et al, 2021_marinedrugs 19 00619 v2.pdf Articolo in rivista MDPI, 1660 3397 Marine drugs Marine drugs Mar. drugs Marine drugs. antonella.leone LEONE ANTONELLA loredana.stabili STABILI LOREDANA lucia.rizzo RIZZO LUCIA GoJelly GoJelly A gelatinous solution to plastic pollution AG.P05.007.001 Biotecnologie per la qualita e sicurezza degli alimenti DBA.AD002.150.001 GoJelly A gelatinous solution to plastic pollution |
