| Title | Anaerobic digestion and removal of sulfamethoxazole, enrofloxacin, ciprofloxacin and their antibiotic resistance genes in a full-scale biogas plant |
| Abstract | Anaerobic digestion is one of the best ways to re-use animal manure and agricultural residues, through the production of combustible biogas and digestate. However, the use of antibiotics for preventing and treating animal diseases and, consequently, their residual concentrations in manure, could introduce them into anaerobic digesters. If the digestate is applied as a soil fertilizer, antibiotic residues and/or their corresponding antibiotic resistance genes (ARGs) could reach soil ecosystems. This work investigated three common soil emerging contaminants, i.e., sulfamethoxazole (SMX), ciprofloxacin (CIP), enrofloxacin (ENR), their ARGs sul1, sul2, qnrS, qepA, aac-(60)-Ib-cr and the mobile genetic element intI1, for one year in a full scale anaerobic plant. Six samplings were performed in line with the 45-day hydraulic retention time (HRT) of the anaerobic plant, by collecting input and output samples. The overall results show both antibiotics and ARGs decreased during the anaerobic digestion process. In particular, SMX was degraded by up to 100%, ENR up to 84% and CIP up to 92%, depending on the sampling time. In a similar way, all ARGs declined significantly (up to 80%) in the digestate samples. This work shows how anaerobic digestion can be a promising practice for lowering antibiotic residues and ARGs in soil. |
| Source | Antibiotics (Basel) 10 (5) |
| Keywords | antibioticsdegradationARGsfluoroquinolonessulfonamidesdigestatezootechnical waste |
| Journal | Antibiotics (Basel) |
| Editor | MDPI, Basel, |
| Year | 2021 |
| Type | Articolo in rivista |
| DOI | 10.3390/antibiotics10050502 |
| Authors | Visca A.; Barra Caracciolo A.; Grenni P.; Patrolecco L.; Rauseo J.; Massini G.; Mazzurco Miritana V; Spataro F. |
| Text | 454663 2021 10.3390/antibiotics10050502 Scopus 2 s2.0 85105794926 antibiotics degradation ARGs fluoroquinolones sulfonamides digestate zootechnical waste Anaerobic digestion and removal of sulfamethoxazole, enrofloxacin, ciprofloxacin and their antibiotic resistance genes in a full scale biogas plant Visca A.; Barra Caracciolo A.; Grenni P.; Patrolecco L.; Rauseo J.; Massini G.; Mazzurco Miritana V; Spataro F. Water Research Institute, National Research Council IRSA CNR , Institute of Polar Sciences, National Research Council ISP CNR , Department of Energy Technologies, Italian National Agency for New Technologies, Energy and Sustainable Economic Development ENEA Anaerobic digestion is one of the best ways to re use animal manure and agricultural residues, through the production of combustible biogas and digestate. However, the use of antibiotics for preventing and treating animal diseases and, consequently, their residual concentrations in manure, could introduce them into anaerobic digesters. If the digestate is applied as a soil fertilizer, antibiotic residues and/or their corresponding antibiotic resistance genes ARGs could reach soil ecosystems. This work investigated three common soil emerging contaminants, i.e., sulfamethoxazole SMX , ciprofloxacin CIP , enrofloxacin ENR , their ARGs sul1, sul2, qnrS, qepA, aac 60 Ib cr and the mobile genetic element intI1, for one year in a full scale anaerobic plant. Six samplings were performed in line with the 45 day hydraulic retention time HRT of the anaerobic plant, by collecting input and output samples. The overall results show both antibiotics and ARGs decreased during the anaerobic digestion process. In particular, SMX was degraded by up to 100%, ENR up to 84% and CIP up to 92%, depending on the sampling time. In a similar way, all ARGs declined significantly up to 80% in the digestate samples. This work shows how anaerobic digestion can be a promising practice for lowering antibiotic residues and ARGs in soil. 10 Published version http //www.scopus.com/record/display.url eid=2 s2.0 85105794926 origin=inward Published paper antibiotics 10 00502.pdf Articolo in rivista MDPI 2079 6382 Antibiotics Basel Antibiotics Basel VISCA ANDREA MAZZURCO MIRITANA VALENTINA luisa.patrolecco PATROLECCO LUISA anna.barracaracciolo BARRA CARACCIOLO ANNA paola.grenni GRENNI PAOLA francesca.spataro SPATARO FRANCESCA jasmin.rauseo RAUSEO JASMIN TA.P04.005.011 Vulnerabilita degli ecosistemi delle acque sotterranee e attenuazione naturale degli inquinanti nel suolo e nel sottosuolo |
