Scheda di dettaglio – i prodotti della ricerca
| Dato | Valore |
|---|---|
| Title | EFFECT OF THE ANTIVIRAL DRUG OSELTAMIVIR (TAMIFLU) ON THE BACTERIAL COMMUNITY STRUCTURE OF A SURFACE WATER ECOSYSTEM ANALYZED BY FLUORESCENCE IN SITU HYBRIDIZATION |
| Abstract | The antiviral drug Tamiflu has received particular attention because of its recommended use against the influenza A H5N1 and H1N1 viruses. Given its resistance to degradation and its hydrophilicity the active metabolite, Oseltamivir Carboxylate (OC), is expected to enter the aquatic ecosystem from sewage treatment plants. In the present paper the bacterial community of surface water samples, treated with OC (1.5 mg L-1), was characterized by Fluorescence In Situ Hybridization (FISH) in microcosm experiments. The alpha-, beta- and gamma-Proteobacteria increased in OC-treated versus non-treated water samples during the incubation period, suggesting these bacterial groups had an active role in OC degradation. |
| Source | Bulletin of environmental contamination and toxicology 85 (5), pp. 443–446 |
| Keywords | PharmaceuticalsTamifluSurface waterFluorescence in situ hybridization |
| Journal | Bulletin of environmental contamination and toxicology |
| Editor | Springer Science and Business Media, New York, NY, Stati Uniti d'America |
| Year | 2010 |
| Type | Articolo in rivista |
| DOI | 10.1007/s00128-010-0114-x |
| Authors | BARRA CARACCIOLO A.; GRENNI P.; SACCÁ M.L. |
| Text | 42405 2010 10.1007/s00128 010 0114 x ISI Web of Science WOS 000284843500001 Pharmaceuticals Tamiflu Surface water Fluorescence in situ hybridization EFFECT OF THE ANTIVIRAL DRUG OSELTAMIVIR TAMIFLU ON THE BACTERIAL COMMUNITY STRUCTURE OF A SURFACE WATER ECOSYSTEM ANALYZED BY FLUORESCENCE IN SITU HYBRIDIZATION BARRA CARACCIOLO A.; GRENNI P.; SACCÁ M.L. Water Research Institute National Research Council, Area della Ricerca di Roma 1 Montelibretti, Via Salaria km 29, 300, CP10 00016 Monterotondo, Rome, Italy The antiviral drug Tamiflu has received particular attention because of its recommended use against the influenza A H5N1 and H1N1 viruses. Given its resistance to degradation and its hydrophilicity the active metabolite, Oseltamivir Carboxylate OC , is expected to enter the aquatic ecosystem from sewage treatment plants. In the present paper the bacterial community of surface water samples, treated with OC 1.5 mg L 1 , was characterized by Fluorescence In Situ Hybridization FISH in microcosm experiments. The alpha , beta and gamma Proteobacteria increased in OC treated versus non treated water samples during the incubation period, suggesting these bacterial groups had an active role in OC degradation. 85 http //dx.doi.org/10.1007/s00128 010 0114 x Articolo Pubblicato BullEnvContTox2010_Tamiflu.pdf Articolo in rivista Springer Science and Business Media 0007 4861 Bulletin of environmental contamination and toxicology Bulletin of environmental contamination and toxicology Bull. environ. contam. toxicol. Bulletin of environmental contamination and toxicology. Bulletin of environmental contamination and toxicology Print anna.barracaracciolo BARRA CARACCIOLO ANNA paola.grenni GRENNI PAOLA TA.P04.005.007 Strumenti di mitigazione dello stress quali quantitativo per i sistemi idrici |