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DatoValore
TitleBiodegradability of pharmaceutical industrial wastewater and formation of recalcitrant organic compounds during aerobic biological treatment
AbstractThe biodegradability of different wastewater samples originated from the industrial production of three pharmaceuticals (naproxen, acyclovir, and nalidixic acid) was performed through the standard Zahn- Wellens test. Moreover, the wastewater composition before and during the test was evaluated in terms of parent compounds and main metabolites by LC/MS, and the biodegradability of the parent compounds was also assessed by performing extra Zahn-Wellens tests on synthetic solutions. The results, besides showing the relatively good biodegradability of acyclovir and naproxen, evidenced the masking role of the organic matrices, especially in the case of nalidixic acid. The latter compound showed to be recalcitrant and persistent, despite the apparently good performance of the Zahn-Wellens test. Deeper evaluation evidenced that the biodegradation of high concentrations of organic solvents and other biodegradable compound tended to ''hide" the lack of removal of the target compound.
SourceBioresource technology 101, pp. 2585–2591
JournalBioresource technology
EditorElsevier Applied Science,, Barking, Regno Unito
Year2010
TypeArticolo in rivista
DOI10.1016/j.biortech.2009.10.057
AuthorsMASCOLO G., BALEST L., CASSANO D., LAERA G., LOPEZ A., POLLICE A., SALERNO C.
Text42358 2010 10.1016/j.biortech.2009.10.057 Biodegradability of pharmaceutical industrial wastewater and formation of recalcitrant organic compounds during aerobic biological treatment MASCOLO G., BALEST L., CASSANO D., LAERA G., LOPEZ A., POLLICE A., SALERNO C. Istituto di Ricerca Sulle Acque, Consiglio Nazionale delle Ricerche, Viale F. De Blasio, 5, 70123 Bari, Italy The biodegradability of different wastewater samples originated from the industrial production of three pharmaceuticals naproxen, acyclovir, and nalidixic acid was performed through the standard Zahn Wellens test. Moreover, the wastewater composition before and during the test was evaluated in terms of parent compounds and main metabolites by LC/MS, and the biodegradability of the parent compounds was also assessed by performing extra Zahn Wellens tests on synthetic solutions. The results, besides showing the relatively good biodegradability of acyclovir and naproxen, evidenced the masking role of the organic matrices, especially in the case of nalidixic acid. The latter compound showed to be recalcitrant and persistent, despite the apparently good performance of the Zahn Wellens test. Deeper evaluation evidenced that the biodegradation of high concentrations of organic solvents and other biodegradable compound tended to hide the lack of removal of the target compound. 101 Biodegradability of pharmaceutical industrial wastewater and formation of recalcitrant organic compounds during aerobic biological treatment 2010_BITE.pdf Articolo in rivista Elsevier Applied Science, 0960 8524 Bioresource technology Bioresource technology Bioresour. technol. Bioresource technology. BALEST LYDIA CASSANO DANIELA alfieri.pollice POLLICE ALFIERI giuseppe.laera LAERA GIUSEPPE antonio.lopez LOPEZ ANTONIO carlo.salerno SALERNO CARLO giuseppe.mascolo MASCOLO GIUSEPPE TA.P07.002.002 Sviluppo di nuovi processi di controllo dell inquinamento idrico.