| Title | Effects of Perfluoralkyl Substances on a Multigenerational Scale: A Case Study with Chironomus riparius (Diptera, Chironomidae) |
| Abstract | A multigenerational test with Chironomus riparius was performed to assess long-term effects on life-traits of exposure to selected perfluoroalkyl compounds: perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and perfluorobutane sulfonate (PFBS). These persistent contaminants are widespread in aquatic ecosystems at low concentrations, possibly exerting long-term toxicity. Larvae of C. riparius of a native population were exposed for 10 generations to 10 ?g/L nominal concentrations of PFOS, PFOA, and PFBS, comparable with the maximum values found in European rivers. All treatments showed reduced growth at most/several generations. No effects on survival, development, and reproduction were found. A final tolerance-induction test was performed exposing the pre-exposed experimental cohorts to 100 µg/L PFOS and 150 µg/L PFOA for a whole life cycle. Factorial analysis of variance revealed no difference between treatments (i.e., PFOS vs PFOA), indicating no induced tolerance. Instead, organisms pre-exposed to PFBS were the most stressed, followed by those pre-exposed to PFOA and PFOS, with earlier emergence and reduced adult weight. The results may be related to general stress and genetic erosion induced by long-term laboratory culture, but also to long-term toxicant exposure. However, no effects at the population level (population growth rate) were proved, and thus a toxicity risk in real ecosystems at the tested concentrations seems unlikely. Environ Toxicol Chem 2019;00:1-12. © 2019 SETAC. |
| Source | Environmental toxicology and chemistry 38, pp. 988–999 |
| Keywords | Multigenerational test; Toxicity; Emerging pollutants; Field-relevant concentrations; Long-term effects; Adaptation |
| Journal | Environmental toxicology and chemistry |
| Editor | Pergamon,, New York, Stati Uniti d'America |
| Year | 2019 |
| Type | Articolo in rivista |
| DOI | 10.1002/etc.4392 |
| Authors | Marziali L.; Rosignoli F.; Valsecchi S.; Polesello S.; Stefani F. |
| Text | 417591 2019 10.1002/etc.4392 Scopus 2 s2.0 85063985918 ISI Web of Science WOS WOS 000465607500007 Multigenerational test; Toxicity; Emerging pollutants; Field relevant concentrations; Long term effects; Adaptation Effects of Perfluoralkyl Substances on a Multigenerational Scale A Case Study with Chironomus riparius Diptera, Chironomidae Marziali L.; Rosignoli F.; Valsecchi S.; Polesello S.; Stefani F. Water Research Institute, Italian National Research Council, Brugherio, Water Research Institute, Italian National Research Council, Brugherio, Italy, , , Italy; Water Research Institute, Italian National Research Council, Brugherio, Water Research Institute, Italian National Research Council, Brugherio, Italy, , , Italy A multigenerational test with Chironomus riparius was performed to assess long term effects on life traits of exposure to selected perfluoroalkyl compounds perfluorooctane sulfonate PFOS , perfluorooctanoic acid PFOA , and perfluorobutane sulfonate PFBS . These persistent contaminants are widespread in aquatic ecosystems at low concentrations, possibly exerting long term toxicity. Larvae of C. riparius of a native population were exposed for 10 generations to 10 g/L nominal concentrations of PFOS, PFOA, and PFBS, comparable with the maximum values found in European rivers. All treatments showed reduced growth at most/several generations. No effects on survival, development, and reproduction were found. A final tolerance induction test was performed exposing the pre exposed experimental cohorts to 100 µg/L PFOS and 150 µg/L PFOA for a whole life cycle. Factorial analysis of variance revealed no difference between treatments i.e., PFOS vs PFOA , indicating no induced tolerance. Instead, organisms pre exposed to PFBS were the most stressed, followed by those pre exposed to PFOA and PFOS, with earlier emergence and reduced adult weight. The results may be related to general stress and genetic erosion induced by long term laboratory culture, but also to long term toxicant exposure. However, no effects at the population level population growth rate were proved, and thus a toxicity risk in real ecosystems at the tested concentrations seems unlikely. Environ Toxicol Chem 2019;00 1 12. © 2019 SETAC. 38 Published version http //www.scopus.com/record/display.url eid=2 s2.0 85063985918 origin=inward paper paper Marziali et al2019 PFAS.pdf Articolo in rivista Pergamon, 0730 7268 Environmental toxicology and chemistry Environmental toxicology and chemistry Environ. toxicol. chem. Environmental toxicology and chemistry ROSIGNOLI FEDERICA PAOLA stefano.polesello POLESELLO STEFANO laura.marziali MARZIALI LAURA fabrizio.stefani STEFANI FABRIZIO saramaria.valsecchi VALSECCHI SARA MARIA |
