| Title | Screening of Chaetomorpha linum lipidic extract as a new potential source of bioactive compounds |
| Abstract | Recent studies have shown that marine algae represent a great source of natural compounds
with several properties. The lipidic extract of the seaweed Chaetomorpha linum (Chlorophyta,
Cladophorales), one of the dominant species in the Mar Piccolo of Taranto (Mediterranean, Ionian
Sea), revealed an antibacterial activity against Vibrio ordalii and Vibrio vulnificus, common pathogens
in aquaculture, suggesting its potential employment to control fish and shellfish diseases due to
vibriosis and to reduce the public health hazards related to antibiotic use in aquaculture. This extract
showed also an antioxidant activity, corresponding to 170.960 16. mmol Trolox equivalent/g
(oxygen radical absorbance capacity assay--ORAC) and to 30.554 2.30 mmol Trolox equivalent/g
(Trolox equivalent antioxidant capacity assay--TEAC). The chemical characterization of the extract,
performed by 1D and 2D NMR spectroscopy, highlighted the presence of free, saturated (SAFAs),
unsaturated (UFAs) and polyunsaturated (PUFAs) fatty acids. The high content of !-6 and !-3
PUFAs confirmed also by gas chromatography indicates the potentiality of this algal species in the
production of fortified food. The antibacterial activity seems related to the presence of linolenic
acid present at high density, while the antioxidant activity could be likely ascribable to molecules
such as carotenoids and chlorophylls (characterized also by thin-layer chromatography), known for
this property. The presence of polyhydroxybutyrate, a biopolymer with potentiality in the field of
biodegradable bioplastics was also detected. The exploitation of C. linum for a future biotechnological
application is also encouraged by the results from a first attempt of cultivating this species in an
integrated multi-trophic aquaculture (IMTA) system |
| Source | Marine drugs 17, pp. 313:1–313:20 |
| Keywords | antibacterial activity; antioxidant activity; NMR spectroscopy; lipidic extract; macroalgae |
| Journal | Marine drugs |
| Editor | MDPI,, Basel, |
| Year | 2019 |
| Type | Articolo in rivista |
| DOI | 10.3390/md17060313 |
| Authors | Loredana Stabili, Maria Immacolata Acquaviva, Federica Angilè, Rosa Anna Cavallo, Ester Cecere, Laura Del Coco, Francesco Paolo Fanizzi, Carmela Gerardi, Marcella Narracci, Antonella Petrocelli |
| Text | 403204 2019 10.3390/md17060313 Scopus 2 s2.0 85075995687 ISI Web of Science WOS A000507340000029 Google Scholar 3Au_35RYKgDlwC ResearchGate 333437298 antibacterial activity; antioxidant activity; NMR spectroscopy; lipidic extract; macroalgae Screening of Chaetomorpha linum lipidic extract as a new potential source of bioactive compounds Loredana Stabili, Maria Immacolata Acquaviva, Federica Angile, Rosa Anna Cavallo, Ester Cecere, Laura Del Coco, Francesco Paolo Fanizzi, Carmela Gerardi, Marcella Narracci, Antonella Petrocelli Institute of Water Research IRSA C.N.R, Department of Science and Biological and Environmental Technologies, University of Salento Institute of Sciences of Food Production ISPA CNR, U.O.S. di Lecce Recent studies have shown that marine algae represent a great source of natural compounds with several properties. The lipidic extract of the seaweed Chaetomorpha linum Chlorophyta, Cladophorales , one of the dominant species in the Mar Piccolo of Taranto Mediterranean, Ionian Sea , revealed an antibacterial activity against Vibrio ordalii and Vibrio vulnificus, common pathogens in aquaculture, suggesting its potential employment to control fish and shellfish diseases due to vibriosis and to reduce the public health hazards related to antibiotic use in aquaculture. This extract showed also an antioxidant activity, corresponding to 170.960 16. mmol Trolox equivalent/g oxygen radical absorbance capacity assay ORAC and to 30.554 2.30 mmol Trolox equivalent/g Trolox equivalent antioxidant capacity assay TEAC . The chemical characterization of the extract, performed by 1D and 2D NMR spectroscopy, highlighted the presence of free, saturated SAFAs , unsaturated UFAs and polyunsaturated PUFAs fatty acids. The high content of 6 and 3 PUFAs confirmed also by gas chromatography indicates the potentiality of this algal species in the production of fortified food. The antibacterial activity seems related to the presence of linolenic acid present at high density, while the antioxidant activity could be likely ascribable to molecules such as carotenoids and chlorophylls characterized also by thin layer chromatography , known for this property. The presence of polyhydroxybutyrate, a biopolymer with potentiality in the field of biodegradable bioplastics was also detected. The exploitation of C. linum for a future biotechnological application is also encouraged by the results from a first attempt of cultivating this species in an integrated multi trophic aquaculture IMTA system 17 Published version https //www.mdpi.com/1660 3397/17/6/313 23/05/2019 STABILI 2019 Screening of Chaetomorpha linum Lavoro pubblicato STABILI 2019 Screening of Chaetomorpha linum.pdf Articolo in rivista MDPI, 1660 3397 Marine drugs Marine drugs Mar. drugs Marine drugs. antonella.petrocelli PETROCELLI ANTONELLA loredana.stabili STABILI LOREDANA carmela.gerardi GERARDI CARMELA mariaimmacolata.acquaviva ACQUAVIVA MARIA IMMACOLATA marcella.narracci NARRACCI MARCELLA ester.cecere CECERE ESTER rosaanna.cavallo CAVALLO ROSA ANNA DTA.AD005.084.002 Utilizzazione di biomasse e sostanze attive da organismi marini |
