Scheda di dettaglio – i prodotti della ricerca
| Dato | Valore |
|---|---|
| Title | Persistence of antibiotic resistance genes in large subalpine lakes: the role of anthropogenic pollution and ecological interactions |
| Abstract | The spread of antibiotic-resistant bacteria is a threatening risk for human health at a global scale. Improved knowledge on the cycle of antibiotic resistance spread between human and the environment is a major requirement for the management of the current crisis. Compared to the well-studied cycle in clinical settings much less is known about the factor allowing their persistence in the environment. In fact, lakes and rivers exposed to high anthropogenic impact seem to become long-term reservoirs for resistance genes. The presence of antibiotic resistance genes (ARGs) within the resident microbiome of large subalpine lakes (i.e. Lake Geneva, Lake Maggiore) has recently been investigated in both the water column and the sediment. These studies suggest a correlation between the abundance of some ARGs and the anthropogenic impact. Within the system, however, abiotic factors and the food-web structure determine the survival of specific bacterial genotypes and thus the resistance genes they harbour. Thus, a growing body of work suggests an important role of ecological interactions in the persistence or elimination of such genes from the environment. This article reviews the current literature regarding the presence of ARGs in subalpine lakes, the impact of anthropogenic pollution on their appearance and the potential role of various ecological interactions on their persistence in the system. |
| Source | Hydrobiologia (The Hague. Print) 824 (1), pp. 93–108 |
| Keywords | Antibiotic resistance genes; Antibioticresistant bacteria; Subalpine lakes; Species interactions; Anthropogenic impact |
| Journal | Hydrobiologia (The Hague. Print) |
| Editor | Kluwer Academic Publishers, Boston, Paesi Bassi |
| Year | 2018 |
| Type | Articolo in rivista |
| DOI | 10.1007/s10750-017-3480-0 |
| Authors | Eckert E.M.; Di Cesare A.; Coci M.; Corno G. |
| Text | 398721 2018 10.1007/s10750 017 3480 0 Scopus 2 s2.0 85040043607 ISI Web of Science WOS 000448578500005 Antibiotic resistance genes; Antibioticresistant bacteria; Subalpine lakes; Species interactions; Anthropogenic impact Persistence of antibiotic resistance genes in large subalpine lakes the role of anthropogenic pollution and ecological interactions Eckert E.M.; Di Cesare A.; Coci M.; Corno G. Microbial Ecology Group, National Research Council Institute of Ecosystem Study CNR ISE , Largo Tonolli 50, Verbania, 28822, , Italy; Microb Co, Viale XX Settembre 45, Catania, , Italy The spread of antibiotic resistant bacteria is a threatening risk for human health at a global scale. Improved knowledge on the cycle of antibiotic resistance spread between human and the environment is a major requirement for the management of the current crisis. Compared to the well studied cycle in clinical settings much less is known about the factor allowing their persistence in the environment. In fact, lakes and rivers exposed to high anthropogenic impact seem to become long term reservoirs for resistance genes. The presence of antibiotic resistance genes ARGs within the resident microbiome of large subalpine lakes i.e. Lake Geneva, Lake Maggiore has recently been investigated in both the water column and the sediment. These studies suggest a correlation between the abundance of some ARGs and the anthropogenic impact. Within the system, however, abiotic factors and the food web structure determine the survival of specific bacterial genotypes and thus the resistance genes they harbour. Thus, a growing body of work suggests an important role of ecological interactions in the persistence or elimination of such genes from the environment. This article reviews the current literature regarding the presence of ARGs in subalpine lakes, the impact of anthropogenic pollution on their appearance and the potential role of various ecological interactions on their persistence in the system. 824 Published version http //www.scopus.com/inward/record.url eid=2 s2.0 85040043607 partnerID=q2rCbXpz Articolo 2018_Hydrobiologia_824_93_108.pdf Articolo in rivista Kluwer Academic Publishers 0018 8158 Hydrobiologia The Hague. Print Hydrobiologia The Hague. Print Hydrobiologia The Hague. Print Hydrobiologia. The Hague. Print Hydrobiologia Dordrecht The Hague. Print Hydrobiologia Boston The Hague. Print Hydrobiologia London The Hague. Print gianluca.corno CORNO GIANLUCA andrea.dicesare DI CESARE ANDREA estermaria.eckert ECKERT ESTER MARIA |