Scheda di dettaglio – i prodotti della ricerca
| Dato | Valore |
|---|---|
| Title | Development and Characterization of a Novel Bioactive Polymer with Antibacterial and Lysozyme-Like Activity |
| Abstract | The development and characterization of a novel bioactive polymer based on the immobilization of glucose oxidase enzyme (GOx) in a polyvinyl alcohol (PVA) film showing antibacterial activity is presented. The PVA-GOx composite material was extensively characterized by UV-vis, X-ray Photoelectron (XPS) spectroscopy and by Fourier Transform Infrared (FTIR) spectroscopy to verify the preservation of enzyme structural integrity and activity. The antimicrobial activity of this composite material against Escherichia coli and Vibrio alginolyticus was assessed. Furthermore the lysozyme-like activity of PVA-GOx was highlighted by a standard assay on Petri dishes employing Micrococcus lysodeikticus cell walls. The findings from this study have implications for future investigations related to the employment of PVA-GOx system as a composite material of pharmaceutical and technological interest. (c) 2013 Wiley Periodicals, Inc. Biopolymers 101: 461-470, 2014. |
| Source | Biopolymers (Print) 101 (5), pp. 461–470 |
| Keywords | antibacterialglucose oxidaselysozyme-like activitypolyvinyl alcoholXPSFTIR |
| Journal | Biopolymers (Print) |
| Editor | John Wiley & Sons, etc.], [New York, etc.,, Stati Uniti d'America |
| Year | 2014 |
| Type | Articolo in rivista |
| DOI | 10.1002/bip.22404 |
| Authors | Guascito, Maria Rachele; Chirizzi, Daniela; Malitesta, Cosimino; Giotta, Livia; Mastrogiacomo, Disma; Valli, Ludovico; Stabili, Loredana |
| Text | 318086 2014 10.1002/bip.22404 ISI Web of Science WOS 000331620800003 antibacterial glucose oxidase lysozyme like activity polyvinyl alcohol XPS FTIR Development and Characterization of a Novel Bioactive Polymer with Antibacterial and Lysozyme Like Activity Guascito, Maria Rachele; Chirizzi, Daniela; Malitesta, Cosimino; Giotta, Livia; Mastrogiacomo, Disma; Valli, Ludovico; Stabili, Loredana University of Salento; University of Salento; Ist Ambiente Marino Costiero CNR UOS Taranto The development and characterization of a novel bioactive polymer based on the immobilization of glucose oxidase enzyme GOx in a polyvinyl alcohol PVA film showing antibacterial activity is presented. The PVA GOx composite material was extensively characterized by UV vis, X ray Photoelectron XPS spectroscopy and by Fourier Transform Infrared FTIR spectroscopy to verify the preservation of enzyme structural integrity and activity. The antimicrobial activity of this composite material against Escherichia coli and Vibrio alginolyticus was assessed. Furthermore the lysozyme like activity of PVA GOx was highlighted by a standard assay on Petri dishes employing Micrococcus lysodeikticus cell walls. The findings from this study have implications for future investigations related to the employment of PVA GOx system as a composite material of pharmaceutical and technological interest. c 2013 Wiley Periodicals, Inc. Biopolymers 101 461 470, 2014. 101 Published version Articolo in rivista John Wiley Sons, etc. 0006 3525 Biopolymers Print Biopolymers Print Biopolymers Print Biopolymers. Print loredana.stabili STABILI LOREDANA TA.P04.029.002 Utilizzazione di biomasse e sostanze attive da organismi marini biotecnologie per loo sviluppo di nuovi bio materiali e composti bioattivi |