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DatoValore
TitlePharmaceuticals in the environment: Biodegradation and effects on natural microbial communities. A review
AbstractEnvironmental microorganisms play a key role in fundamental ecological processes such as biogeochemical cycling and organic contaminant degradation. Microorganisms comprise a large unexplored reservoir of genetic diversity and metabolic capability providing several ecosystem services, most importantly the maintenance of soil and water quality. Pharmaceutical occurrence in the environment can compromise microbial community structure and activities in different ways. The fate of a pharmaceutical in soil or water depends on numerous factors, including its inherent physic-chemical properties (e.g. water solubility, lipophilicity, vapour pressure), environmental factors and climate conditions (e.g. temperature, incident radiation, pH) and most importantly the presence and activity of microorganisms that possess the ability to biodegrade it. The presence of a natural microbial community is a necessary prerequisite for an effective response to the various chemicals that can contaminate an ecosystem. The recovery from contamination is only possible if toxicity does not hamper microbial activity. This review presents current knowledge on the effects on natural microbial communities of some pharmaceuticals and of some biocides commonly found as environmental microcontaminants.
SourceJournal of pharmaceutical and biomedical analysis (Print) 106, pp. 25–36
KeywordsAnalgesicsAntidepressantsAntiepilepticsBlood lipid regulatorsMicrobicides
JournalJournal of pharmaceutical and biomedical analysis (Print)
EditorElsevier Science, Amsterdam, Paesi Bassi
Year2015
TypeArticolo in rivista
DOI10.1016/j.jpba.2014.11.040
AuthorsBarra Caracciolo A, Topp E, Grenni P
Text297006 2015 10.1016/j.jpba.2014.11.040 Scopus 2 s2.0 84923381210 Analgesics Antidepressants Antiepileptics Blood lipid regulators Microbicides Pharmaceuticals in the environment Biodegradation and effects on natural microbial communities. A review Barra Caracciolo A, Topp E, Grenni P Istituto di Ricerca sulle Acque, Consiglio Nazionale delle Ricerche, Via Salaria km 29,300, Monterotondo, 00015 Rome, Italy; Agriculture and Agri Food Canada, 1391 Sandford Street, London, ON Canada N5 V 4T3 Environmental microorganisms play a key role in fundamental ecological processes such as biogeochemical cycling and organic contaminant degradation. Microorganisms comprise a large unexplored reservoir of genetic diversity and metabolic capability providing several ecosystem services, most importantly the maintenance of soil and water quality. Pharmaceutical occurrence in the environment can compromise microbial community structure and activities in different ways. The fate of a pharmaceutical in soil or water depends on numerous factors, including its inherent physic chemical properties e.g. water solubility, lipophilicity, vapour pressure , environmental factors and climate conditions e.g. temperature, incident radiation, pH and most importantly the presence and activity of microorganisms that possess the ability to biodegrade it. The presence of a natural microbial community is a necessary prerequisite for an effective response to the various chemicals that can contaminate an ecosystem. The recovery from contamination is only possible if toxicity does not hamper microbial activity. This review presents current knowledge on the effects on natural microbial communities of some pharmaceuticals and of some biocides commonly found as environmental microcontaminants. 106 Published version http //www.scopus.com/inward/record.url eid=2 s2.0 84919480500 partnerID=q2rCbXpz Pharmaceuticals in the environment Biodegradation and effects on natural microbial communities. A review articolo pubblicato JPBAPharmBiodegradationReview2015 0.pdf Articolo in rivista Elsevier Science 0731 7085 Journal of pharmaceutical and biomedical analysis Print Journal of pharmaceutical and biomedical analysis Print J. pharm. biomed. anal. Print Journal of pharmaceutical biomedical analysis. Print Journal of pharmaceutical and biomedical analysis Print anna.barracaracciolo BARRA CARACCIOLO ANNA paola.grenni GRENNI PAOLA TA.P04.005.011 Vulnerabilita degli ecosistemi delle acque sotterranee e attenuazione naturale degli inquinanti nel suolo e nel sottosuolo