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DatoValore
TitleUnexpected dose response of repeated annual veterinary drug applications on microbial diversity and functions in an agricultural soil
AbstractAntibiotics are widely used in North American and Asian livestock and poultry production for growth promotion, prophylaxis and treatment of illness. There is a widespread concern that this practice promotes resistance and erodes the efficacy of antibiotics used in human medicine, a crucially important public health challenge. It is unknown if concentrations of antibiotics released through livestock production are sufficient to promote resistance in environmental bacteria. A reservoir of antibiotic resistance genes in the environment that is made larger through contamination with agricultural wastes may represent an enhanced threat to human health. Within this context we have been exploring the long-term impacts of selected veterinary antibiotics on soil microbial populations. A series of replicated plots were established in London, Ontario, Canada in 1999 that have since been treated once annually every spring with a mixture of sulfamethazine, tylosin and chlortetracycline. The drug mixture was applied to achieve a range of soil concentrations (0, 0.1, 1.0, 10.0 mg of each drug per kg soil) encompassing that which would be expected from a typical rate of annual application of manure from a commercial swine farm. The antibiotics were added to the soil without the addition of manure in order to directly evaluate the impacts of the drugs on soil microorganisms without a confounding effect from the enteric flora shed by animals.
Source23rd SETAC Europe Annual Meeting, Glasgow (GB), 12-16 May 2013
Keywordsantibiotic resistancesoil microbila communitylong-term exposure to veterinary antibiotics
Year2013
TypePresentazione
AuthorsTopp E, Scott A, Sabourin L, Grenni P, Barra Caracciolo A, Marti R
Text226787 2013 antibiotic resistance soil microbila community long term exposure to veterinary antibiotics Unexpected dose response of repeated annual veterinary drug applications on microbial diversity and functions in an agricultural soil Topp E, Scott A, Sabourin L, Grenni P, Barra Caracciolo A, Marti R Topp E, Scott A, Sabourin L, Marti R Agriculture and Agri Food Canada, London ON Canada N5V 4T3 Grenni P, Barra Caracciolo A IRSA CNR Antibiotics are widely used in North American and Asian livestock and poultry production for growth promotion, prophylaxis and treatment of illness. There is a widespread concern that this practice promotes resistance and erodes the efficacy of antibiotics used in human medicine, a crucially important public health challenge. It is unknown if concentrations of antibiotics released through livestock production are sufficient to promote resistance in environmental bacteria. A reservoir of antibiotic resistance genes in the environment that is made larger through contamination with agricultural wastes may represent an enhanced threat to human health. Within this context we have been exploring the long term impacts of selected veterinary antibiotics on soil microbial populations. A series of replicated plots were established in London, Ontario, Canada in 1999 that have since been treated once annually every spring with a mixture of sulfamethazine, tylosin and chlortetracycline. The drug mixture was applied to achieve a range of soil concentrations 0, 0.1, 1.0, 10.0 mg of each drug per kg soil encompassing that which would be expected from a typical rate of annual application of manure from a commercial swine farm. The antibiotics were added to the soil without the addition of manure in order to directly evaluate the impacts of the drugs on soil microorganisms without a confounding effect from the enteric flora shed by animals. Building a Better future responsible innovation and environmental protection SETAC EUROPE 978 1 63266 509 6 http //glasgow.setac.eu/home/ contentid=570 pr_id=569 23rd SETAC Europe Annual Meeting Glasgow GB 12 16 May 2013 Internazionale Contributo Presentazione_pubblicata Long Abstract 2013_abstract_extended_SETAC_Glasgow_Topp_etal.pdf Presentazione anna.barracaracciolo BARRA CARACCIOLO ANNA paola.grenni GRENNI PAOLA TA.P04.005.011 Vulnerabilita degli ecosistemi delle acque sotterranee e attenuazione naturale degli inquinanti nel suolo e nel sottosuolo