| Title | First insights into the biochemistry of Sabella spallanzanii (Annelida: Polychaeta) mucus: a potentially unexplored resource for applicative purposes |
| Abstract | Although mucus plays many different roles among marine invertebrates, relatively little is known about the link between biochemical
structure and function. In the present study we focused on some physical and chemical properties of the polychaete
Sabella spallanzanii's mucus such as viscosity, osmolarity, electrical conductivity, elemental composition, the protein and
carbohydrate content, the total lipids and fatty acid composition, and polychlorinated biphenyls (PCBs) contamination.
Moreover, an antimicrobial activity of the mucus was investigated. The water content of S. spallanzanii mucus was
96.2+0.3%. By dry weight 26+1.2% was protein, 8+0.21% was carbohydrate and only 0.1% lipid, much of the remainder
of the dry weight was inorganic (about 65.2%). The estimated PCBs content was ,0.005 mg g21. The mucus of S. spallanzanii
exerted a natural lysozyme-like activity and produced in vitro the growth inhibition of Vibrio anguillarum, Vibrio harveyi,
Pseudomonas aeruginosa and Candida albicans. The findings from this study contribute to improve the limited knowledge
available on the mucus composition in invertebrates and have implications for future investigations related to employment of
S. spallanzanii mucus as a source of compounds of pharmaceutical and marine technological interest |
| Source | Journal of the Marine Biological Association of the UK (Online) 91 (1), pp. 199–208 |
| Keywords | mucuslipidsPCBslysozymeantimicrobial activity |
| Journal | Journal of the Marine Biological Association of the UK (Online) |
| Editor | Cambridge University Press., Cambridge, Regno Unito |
| Year | 2011 |
| Type | Articolo in rivista |
| DOI | 10.1017/S0025315410001013 |
| Authors | STABILI L.,SCHIROSI R., DI BENEDETTO A., MERENDINO A., VILLANOVA L., GIANGRANDE A. |
| Text | 215289 2011 10.1017/S0025315410001013 ISI Web of Science WOS WOS 000287282500019 mucus lipids PCBs lysozyme antimicrobial activity First insights into the biochemistry of Sabella spallanzanii Annelida Polychaeta mucus a potentially unexplored resource for applicative purposes STABILI L.,SCHIROSI R., DI BENEDETTO A., MERENDINO A., VILLANOVA L., GIANGRANDE A. IAMC, CNR U.O.S. di Taranto DiSteBa, Universita del Salento CIRCC Bari LACHIFARMA srl Although mucus plays many different roles among marine invertebrates, relatively little is known about the link between biochemical structure and function. In the present study we focused on some physical and chemical properties of the polychaete Sabella spallanzanii s mucus such as viscosity, osmolarity, electrical conductivity, elemental composition, the protein and carbohydrate content, the total lipids and fatty acid composition, and polychlorinated biphenyls PCBs contamination. Moreover, an antimicrobial activity of the mucus was investigated. The water content of S. spallanzanii mucus was 96.2 0.3%. By dry weight 26 1.2% was protein, 8 0.21% was carbohydrate and only 0.1% lipid, much of the remainder of the dry weight was inorganic about 65.2% . The estimated PCBs content was ,0.005 mg g21. The mucus of S. spallanzanii exerted a natural lysozyme like activity and produced in vitro the growth inhibition of Vibrio anguillarum, Vibrio harveyi, Pseudomonas aeruginosa and Candida albicans. The findings from this study contribute to improve the limited knowledge available on the mucus composition in invertebrates and have implications for future investigations related to employment of S. spallanzanii mucus as a source of compounds of pharmaceutical and marine technological interest 91 Published version Articolo in rivista Cambridge University Press. 1469 7769 Journal of the Marine Biological Association of the UK Online Journal of the Marine Biological Association of the UK Online J. Mar. Biol. Assoc. UK Online JMBA Online Online Journal of the Marine Biological Association of the United Kingdom Online Online loredana.stabili STABILI LOREDANA TA.P04.029.002 Utilizzazione di biomasse e sostanze attive da organismi marini biotecnologie per loo sviluppo di nuovi bio materiali e composti bioattivi |
