Emerging MS-based platforms for the characterization of tumor-derived exosomes isolated from human biofluids: challenges and promises of MudPIT

Ferrari, Emanuele; De Palma, Antonella; Mauri, Pierluigi

Articolo in rivista: Expert review of proteomics (Print) 14 (9), pp. 757–767
Keywords: Cancer; exosomes; urine; plasma; proteomics; LC-MS/MS; MudPIT

DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function

Plotegher N, Berti G, Ferrari E, Tessari I, Zanetti M, Lunelli L, Greggio E, Bisaglia M, Veronesi M, Girotto S, Dalla Serra M, Perego C, Casella L, Bubacco L

Articolo in rivista: Scientific reports (Nature Publishing Group) 7
Keywords: Toxic dopamine metabolite; Parkinsons-disease; Recycling-pool; Membrane; Aldehyde; 3; 4-Dihydroxyphenylacetaldehyde; Cells; Pathogenesis; Homeostasis

Neuromelanin-sensitive MRI as a proxy-measure of dopamine function in neuropsychiatric illness.

Cassidy C.; Zecca L.; Ferrari E.; Zucca F.A.; Weinstein J.; Baker S.; Benavides C.; Kang U.; Sulzer D.; Abi-Dargham A.; Horga G.

Poster: Dopamine 2016, Campus of the University of Vienna, Vienna, Austria, 5-8/09/2016
Keywords: neuromelanin; MRI; dopamine; neuropsychiatric illness

Application of Pump-Probe Imaging Towards Chemical and Structural Characterization of Neuromelanin.

Deb S.; Ferrari E.; Zucca F.A.; Zecca L.; Warren W.S.

Poster: World Molecular Imaging Congress (WMIC) 2016, New York, NY, USA, 7-10/09/2016
Keywords: Pump-Probe Imaging; neuromelanin

The role of neuromelanins in the oxidative stress of Parkinson's disease.

Zecca L, Isaias I, Casella L, Capucciati A, Ferrari E, Horga G, Cassidy C, Sulzer D and Zucca FA

Poster: Xth International Workshop on EPR in Biology and Medicine, Krakow, Poland, 2-6/10/2016
Keywords: neuromelanin; oxidative stress; parkinson disease

Contrast mechanisms associated with neuromelanin-MRI

Trujillo P.; Summers P.E.; Ferrari E.; Zucca F.A.; Sturini M.; Mainardi L.T.; Cerutti S.; Smith A.K.; Smith S.A.; Zecca L.; Costa A.

Articolo in rivista: Magnetic resonance in medicine (Print) 78 (5), pp. 1790–1800
Keywords: neuromelanin; MRI; magnetization transfer; relaxation

Synthesis, Structure Characterization, and Evaluation in Microglia Cultures of Neuromelanin Analogues Suitable for Modeling Parkinson's Disease

Ferrari E.; Capucciati A.; Prada I.; Zucca F.A.; D'Arrigo G.; Pontiroli D.; Bridelli M.G.; Sturini M.; Bubacco L.; Monzani E.; Verderio C.; Zecca L.; Casella L.

Articolo in rivista: ACS chemical neuroscience 8 (3), pp. 501–512
Keywords: neuromelanin; iron; amyloid fibrils; synthetic melanin; microglia; Parkinson's disease

Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

Zucca F.A.; Segura-Aguilar J.; Ferrari E.; Muñoz P.; Paris I.; Sulzer D.; Sarna T.; Casella L.; Zecca L.

Articolo in rivista: Progress in neurobiology (Print) 155, pp. 96–119
Keywords: iron; dopamine; melanin; human neuromelanin; Parkinson's disease

Neuromelanin of the Human Substantia Nigra: An Update

Zucca F.A.; Basso E.; Cupaioli F.A.; Ferrari E.; Sulzer D.; Casella L.; Zecca L.

Articolo in rivista: Neurotoxicity resarch 25 (1), pp. 13–23
Keywords: neuromelanin; substantia nigra; Parkinson's disease; aging; neuroinflammation; neurodegeneration

Protective and toxic roles of dopamine in Parkinson's disease

Segura-Aguilar J.; Paris I.; Muñoz P.; Ferrari E.; Zecca L.; Zucca F.A.

Articolo in rivista: Journal of neurochemistry 129 (6), pp. 898–915
Keywords: 5 6-indolequinone; aminochrome; dopamine; dopamine o-quinone; neurodegeneration; neuromelanin; Parkinson's disease

Synthetic models of neuromelanin with fibrillated protein in the core

Ferrari E.; Capucciati A.; Monzani E.; Sturini M.; Girotto S.; Zucca F.A.; Bubacco L.; Zecca L.; Casella L.

Poster: FENS 2014 - NTS Satellite Symposium, Baveno, Italy, July, 10th-11th, 2014
Keywords:

Melanin-protein fibrils conjugates as models to study neuromelanin structure and reactivity.

Capucciati A.; Ferrari E.; Monzani E.; Sturini M.; Girotto S.; Zucca F.A.; Bridelli M.G.; Bubacco L.; Zecca L.; Casella L.

Poster: Zing Conference on Oxidative Stress, Parador de Oropesa, Spain, October 3 - 6, 2014
Keywords:

The role of neuromelanin organelle pathways in parkinson's disease

Zecca L.; Cebrián C.; Ferrari E.; Bellei C.; Cupaioli F.A.; De Palma A.; Mauri P.; Casella L.; Sulzer D.; Zucca F.A.

Abstract in atti di convegno: Multiple mechanisms of neurodegeneration and progression, Milano FENS 2014 - NTS Satellite Symposium, Baveno, Italy, July 10 - 11, 2014
Keywords:

Neuromelanin organelles pathways in brain aging and Parkinson's disease

Zecca L.; Ferrari E.; Bellei C.; Mauri P.; Casella L.; Sarna T.; Zucca F.A.

Abstract in atti di convegno: Zing Conference on Oxidative Stress, Parador de Oropesa, Spain, October 3 - 6, 2014
Keywords:

Neuromelanin organelle pathways in aging and neurodegeneration of Parkinson's Disease

Zecca L.; Cupaioli F.A.; Bellei C.; Ferrari E.; Mauri P.; Sulzer D.; Zucca F.A.

Poster: Annual Meeting of the CNR Aging program 2012-2014 during '9th Congress of the European Union Geriatric Medicine Society - EUGMS', Lido di Venezia, Italy, October 2-4, 2013
Keywords:

NEUROMELANINS ACCUMULATE IN NEURONS DURING HUMAN BRAIN AGING AND BIND METALS

Zecca L.; Bellei C.; Ferrari E.; Bubacco L.; Casella L.; Zucca F.A.

Abstract in atti di convegno: Biomet 13 - XIII Workshop on PharmacoBioMetallics, Catania (Italy), October 25 and 26, 2013
Keywords:

Urinary proteomics profiles are useful for detection of cancer biomarkers and changes induced by therapeutic procedures

Ferrari E.; Wittig A.; Basilico F.; Rossi R.; De Palma A.; Di Silvestre D.; Sauerwein W.A.G.; Mauri P.L.

Articolo in rivista: Molecules (Basel, Online) 24 (4)
Keywords: BNCT; LC-MS; MudPIT; boron; proteomics; squamous cell cancer of head and neck; thyroid cancer; urine

Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis.

Ferrari E.; Engelen M.; Monzani E.; Sturini M.; Girotto S.; Bubacco L.; Zecca L.; Casella L.

Articolo in rivista: JBIC. Journal of biological inorganic chemistry (Print) 18 (1), pp. 81–93
Keywords:

Effective high-throughput isolation of enriched platelets and circulating pro-angiogenic cells to accelerate skin-wound healing

Erratico, Silvia; Belicchi, Marzia; Meregalli, Mirella; Di Silvestre, Dario; Tripodi, Luana; De Palma, Antonella; Jones, Rebecca; Ferrari, Emanuele; Porretti, Laura; Trombetta, Elena; Merlo, Giorgio R.; Mauri, Pierluigi; Torrente, Yvan

Articolo in rivista: Cellular and molecular life sciences (Print. ed.) 79 (5)
Keywords: Epithelialization; PRP; Angiogenic potential; Skin remodeling; Proteomics